Ethyl 4-nitrobutanoate
CAS: 2832-16-8
Ref. 3D-CAA83216
1g | Discontinued | ||
5g | Discontinued | ||
10g | Discontinued | ||
100mg | Discontinued | ||
250mg | Discontinued | ||
500mg | Discontinued |
Product Information
Ethyl 4-nitrobutanoate is an organic compound belonging to the group of nitro compounds. It is a colorless liquid with a strong odor that can be synthesized from sulfinyl acetone and nitromethane. The reaction occurs by nucleophilic addition of the sulfinyl group to the nitro group, followed by elimination of water. This process is stereospecific, meaning that only one stereoisomer can form. The product obtained in this reaction is enantioenriched because it contains one optical isomer and one racemic mixture. The main application of this compound is in the transformation of lactams into chiral lactams, which are important for pharmaceuticals and agrochemicals. These reactions are catalyzed by intramolecular aldimines or conjugative agents such as 1,3-dipoles or 1,2-dipoles.