GIBH-130
CAS: 1252608-59-5
Ref. 3D-CAC60859
5mg | Discontinued | ||
10mg | Discontinued | ||
25mg | Discontinued | ||
50mg | Discontinued | ||
100mg | Discontinued |
Product Information
GIBH-130 is a potent, novel small molecule inhibitor of proinflammatory cytokines that targets the protein targets IL-1β and IL-6. In vivo efficacy has been demonstrated in murine models of CNS inflammation. GIBH-130 is a potential therapeutic for neuroinflammation and neuronal death due to its inhibition of proinflammatory cytokines. This drug also inhibits amyloid precursor protein (APP) processing and blocks the release of Aβ peptides in vitro. GIBH-130 may be an effective treatment for Alzheimer's disease as it inhibits proinflammatory cytokines, which are implicated in the etiology of this disease.