Product Information
- Hexamethyleneiminocarbonyl chloride
- N,N-Hexamethylenecarbamoyl chloride
- 1H-Azepine-1-carbonyl chloride, hexahydro-
- N-Chlorocarbonylhexamethylenimine
- Hexahydro-1H-azepine-1-carbonyl chloride
Azepane-1-carbonyl chloride is a molecule that has been shown to be efficacious in the treatment of trypanosomiasis. It is a urea derivative that works by inhibiting the activity of a specific enzyme, adenylate kinase, which is essential for the metabolism of nucleotides and nucleosides. Azepane-1-carbonyl chloride binds to this enzyme and prevents it from converting ATP into AMP, which leads to cell death. This molecule has been shown to have antiviral properties against murine leukemia virus and trypanosoma cruzi. However, it does not seem to work as well on human cells. The efficacy of azepane-1-carbonyl chloride in vivo has also been demonstrated using an animal model. The effects of this molecule are dose dependent and there may be potential for optimization by changing its structure or metabolic stability.
Chemical properties
Technical inquiry about: 3D-CBA81735 Azepane-1-carbonyl chloride
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