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2-Amino-4-phenylthiazole hydrobromide monohydrate
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2-Amino-4-phenylthiazole hydrobromide monohydrate

CAS: 52253-69-7

Ref. 3D-CCA25369

100gDiscontinued

Discontinued product. For inquiries about similar products, please fill out our form or email us at support@cymitquimica.com.


Product Information

Name:
2-Amino-4-phenylthiazole hydrobromide monohydrate
Synonyms:
  • 4-Phenylthiazol-2-Ylamine Hydrobromide Monohydrate
  • 4-Phenyl-1,3-thiazol-2-amine
  • 4-Phenyl-1,3-Thiazol-2-Amine Hydrobromide Hydrate
Description:

2-Amino-4-phenylthiazole hydrobromide monohydrate (2APT) is an inhibitor of histone deacetylase. It was synthesized by reacting 2-amino-4-phenylthiazole with hydrobromic acid, and the resulting salt was obtained as a white solid. The structure of 2APT has been determined by X-ray crystallography. The compound is a hydrogen bond donor and a strong hydrophobic ligand, which may be responsible for its binding to the active site of HATs.
2APT inhibits the activity of HATs by forming a covalent bond with the catalytic cysteine residue in the active site. This inhibition leads to decreased acetylation of histones, which results in changes in gene expression and ultimately cell growth arrest or apoptosis.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
275.17 g/mol
Formula:
C9H8N2S·HBr·H2O
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

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Inquiry about discontinued product: 3D-CCA25369 2-Amino-4-phenylthiazole hydrobromide monohydrate

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