Phellamurin
CAS: 52589-11-4
Ref. 3D-CCA58911
| 5mg | Discontinued | ||
| 10mg | Discontinued | ||
| 25mg | Discontinued | ||
| 50mg | Discontinued | ||
| 100mg | Discontinued |
Product Information
- (2R,3R)-7-(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)-2,3-dihydro-3,5-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
- 4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-2,3-dihydro-3,5-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-, (2R-trans)-
- 4H-1-Benzopyran-4-one, 7-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-2,3-dihydro-3,5-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-, (2R,3R)-
- 4H-1-Benzopyran-4-one, 7-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-2,3-dihydro-3,5-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-, (2R,3R)-
- 4H-1-Benzopyran-4-one, 7-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-2,3-dihydro-3,5-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-, (2R-trans)-
- Fellavin
- Flacoside
Phellamurin is a diterpene from the bark of the tree Phellodendron amurense. This compound has been shown to have various physiological activities, including antioxidant, anti-inflammatory and antimicrobial effects. Phellamurin inhibits lipid peroxidation by inhibiting the formation of free radicals, which are believed to be the cause of lipid peroxidation. In addition, phellamurin has been shown to inhibit the growth of cancer cells in vitro and in vivo. A chromatographic method was used to isolate phellamurin and other related compounds from P. amurense. The prenyl group found on phellamurin is responsible for its antioxidant activity as well as its inhibition of tumor cell proliferation and DNA synthesis. The hydroxyl group on this molecule also plays an important role in its biological activity by acting as a hydrogen donor for fatty acid synthase or desaturase enzymes involved in lipid metabolism.
