7-Desmethylagomelatine
CAS: 152302-45-9
Ref. 3D-CGA30245
5mg | Discontinued | ||
10mg | Discontinued | ||
25mg | Discontinued | ||
50mg | Discontinued | ||
100mg | Discontinued |
Product Information
- Acetamide, N-[2-(7-hydroxy-1-naphthalenyl)ethyl]-
7-Desmethylagomelatine is a drug candidate for the treatment of functional gastrointestinal disorders. It is an analog of melatonin, and has been shown to be efficacious in healthy Chinese subjects. 7-Desmethylagomelatine is rapidly absorbed from the gut and exhibits linear pharmacokinetics with dose. The drug also binds to 5-HT2C receptors, which are involved in the regulation of sleep and appetite. A recent study has validated that 7-desmethylagomelatine is bioequivalent to standard melatonin in healthy Chinese subjects.