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Lomitapide mesylate
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Lomitapide mesylate

CAS: 202914-84-9

Ref. 3D-CIA91484

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Estimated delivery in United States, on Friday 16 Aug 2024

Product Information

Name:
Lomitapide mesylate
Synonyms:
  • 9H-Fluorene-9-carboxamide, N-(2,2,2-trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]car bonyl]amino]-1-piperidinyl]butyl]-, methanesulfonate
  • 9H-Fluorene-9-carboxamide, N-(2,2,2-trifluoroethyl)-9-[4-[4-[[[4′-(trifluoromethyl)[1,1′-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-, methanesulfonate
  • 9H-Fluorene-9-carboxamide, N-(2,2,2-trifluoroethyl)-9-[4-[4-[[[4′-(trifluoromethyl)[1,1′-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-, methanesulfonate (1:?)
  • BMS 201038 methanesulfonic acid salt
  • Bms 201038-04
  • Juxtapid
Description:

Lomitapide mesylate is a drug used to treat familial hypercholesterolemia. It is an ATP-binding cassette transporter inhibitor and can be used to lower cholesterol levels in patients with homozygous familial hypercholesterolemia. Lomitapide mesylate has been shown to reduce LDL-C levels by up to 50% in patients with this condition. The drug has a number of side effects, such as skin cancer, which may be due to the inhibition of chemoattractant protein signalling pathways. Side effects are usually mild and transient, but may include hepatic dysfunction and metabolic disorders. Lomitapide mesylate is metabolized by CYP3A4 enzyme and its plasma concentration may be increased if taken concurrently with drugs that inhibit this enzyme (e.g., diltiazem).

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
789.83 g/mol
Formula:
C40H41F6N3SO5
Purity:
Min. 95%
MDL:
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Flash point:
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Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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