Neurokinin B (human, porcine)
Ref. 3D-CRB1000581
| 1mg | 183.00 € | ||
| 500µg | 134.00 € |
Product Information
- DMHDFFVGLM-amideH-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2
Neurokinin B (NKB) is a member of the tachykinin family of peptides that include substance P (SP), neurokinin A (NKA), endokinins and haemokinins. NKB is encoded by TAC3 in humans and Tac2 in rodents and along with the neuropeptide kisspeptin plays an essential role as gatekeeper of puberty.NKB plays a stimulatory role in luteinising hormone (LH) release in a number of species, likely mediated via the secretion of gonadotropin-releasing hormone (GnRH) in a kisspeptin-dependent manner (NKB appears to play a critical role in the control of kisspeptin release). NKB may contribute to the regulation of reproductive functions by metabolic cues. NKB binds with highest affinity to the G-protein coupled neurokinin-3 receptor NK3R also known as tachykinin receptor 3 (TACR3)
Chemical properties
Technical inquiry about: 3D-CRB1000581 Neurokinin B (human, porcine)
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