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[Des-Arg9]-Bradykinin Heavy
Ref. 3D-CRB1300683
| 25nMol | 379.00 € |
Product Information
- RPPG-[U-13C9,15N-Phe]-SPF-acidH-Arg-Pro-Pro-Gly-[U-13C9,15N-Phe]-Ser-Pro-Phe-OH
[Des-Arg9]-Bradykinin Heavy-is a metabolite of des-Arg(9)kinin and its production is increased upon inflammation.-[Des-Arg9]-Bradykinin Heavy acts on the bradykinin B(1) receptor as a potent and highly selective receptor agonist.The bradykinin receptor B1Rs is a heterotrimeric G-protein coupled receptor which regulates migration of microglia and T cells. The expression of the B(1) receptor is induced in various inflammatory conditions, and may play an important role in modulating cardiovascular function.The phenylalanine-residue at position 5 of this peptide is isotopically labelled with Carbon-13 (9) and Nitrogen-15 (1).
Chemical properties
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