ONO-8590580
CAS: 1802661-73-9
Ref. 3D-CXC66173
| 1mg | To inquire | |
| 5mg | To inquire | |
| 10mg | To inquire | |
| 25mg | To inquire | |
| 50mg | To inquire |
Product Information
ONO-8590580 is a potentiator of cholinergic neurotransmission. It binds to the acetylcholine binding site of alpha7 nicotinic receptor subunit, and the activation of this receptor enhances acetylcholine release in hippocampal cells. ONO-8590580 has been shown to be an allosteric modulator of alpha7 nicotinic receptors, which may lead to increased levels of acetylcholine in the brain. This drug also inhibits benzodiazepine binding, which may contribute to its cognitive enhancement effects. It has been shown that ONO-8590580 can increase the expression of wild type mice and is optimised for oral use. The drug is currently in phase I clinical trials for Alzheimer's disease and other neurodegenerative disorders.
Chemical properties
Technical inquiry about: 3D-CXC66173 ONO-8590580
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