Product Information
- 1-(Iodomethyl)-4-Nitrobenzene
- 4-Nitrobenzyl iodide
- Ai3-50469
- Benzene, 1-(iodomethyl)-4-nitro-
- NSC 401699
- Toluene, α-iodo-p-nitro-
- alpha-Iodo-p-nitrotoluene
- p-Nitro-α-iodotoluene
p-Nitrobenzyl iodide is an organic compound that is used as an alkylating agent. It reacts with amino groups in proteins by substitution of the nitrogen atom with a methylene group. This reaction requires the presence of glutathione, which acts as a cofactor and provides a chloride ion to facilitate the formation of the reactive intermediate. p-Nitrobenzyl iodide also binds covalently to DNA and causes cross-linking, leading to inhibition of DNA replication and transcription. p-Nitrobenzyl iodide has been shown to have inhibitory effects on mycocerosic activity in vitro and in vivo.
Chemical properties
Technical inquiry about: 3D-DAA14586 p-Nitrobenzyl iodide
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