1,2-Didecanoyl-sn-glycero-3-phosphocholine

CAS: 3436-44-0

Ref. 3D-DAA43644

Product Information

• Name: 1,2-Didecanoyl-sn-glycero-3-phosphocholine
• Synonyms: L-Didecanoyllecithin, (2R)-2,3-bis(decanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate, (R)-2,3-Bis(decanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate, 3,5,9-Trioxa-4-phosphanonadecan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxodecyl)oxy]-, inner salt, 4-oxide, (7R)-, 3,5,9-Trioxa-4-phosphanonadecan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxodecyl)oxy]-, inner salt, 4-oxide, (R)-, <span class="text-smallcaps">L</span>-Dicapryllecithin, <span class="text-smallcaps">L</span>-Didecanoyllecithin, <span class="text-smallcaps">L</span>-Didecanoylphosphatidylcholine, <span class="text-smallcaps">L</span>-α-Didecanoylphosphatidylcholine, Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-didecanoin, <span class="text-smallcaps">L</span>-, Coatsome MC 1010, Decanoin, 1,2-di-, dihydrogen phosphate, monoester with choline hydroxide inner salt, <span class="text-smallcaps">L</span>-, Didecanoyl-<span class="text-smallcaps">L</span>-α-glycerophosphorylcholine, Didecanoyl-<span class="text-smallcaps">L</span>-α-phosphatidycholine, Didecanoylglycerophosphocholine, Didecanoyllecithin, Didecanoylphosphatidylcholine, L-a-Lecithin-dicaproyl = L-a-Dicaproyl Lecithin = L-a-Dicapryl Lecithin = L-a-Dicaprylyl Lecithin, Pc(10:0/10:10)

Description

1,2-Didecanoyl-sn-glycero-3-phosphocholine (DDPC) is a phospholipid that is used as an absorption enhancer. DDPC has been shown to have inhibitory effects on propranolol hydrochloride and p-glycoprotein (Pgp). It binds to the Pgp substrate site and blocks the transport of drugs in the cell membrane. This drug is also a model system for studying the hydrophobic effect of phospholipids. The phase transition temperature for DDPC is about 40°C, which indicates its hydrophilic nature. The acyl chain length of this lipid determines its phase transition temperature at different temperatures.

• Brand: Biosynth

Chemical properties

• Molecular weight: 565.72 g/mol
• Formula: C₂₈H₅₆NO₈P
• Purity: Min. 95%
• Color/Form: Powder