Pyrvinium pamoate

CAS: 3546-41-6

Ref. 3D-DAA54641

Product Information

• Name: Pyrvinium pamoate
• Synonyms: 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-, ion(2-), bis[6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methylquinolinium], 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, ion(2-), bis[6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methylquinolinium], 6-(dimethylamino)-2-[(E)-2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methylquinolinium 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylate, 6-Dimethylamino-2-[2-(2,5-dimethyl-1-phenyl-3-pyrryl)vinyl]-1-methylquinolinium salt of 2,2′-dihydroxy-1,1′-dinaphthylmethane-3,3′-dicarboxylic acid, Alnoxin, Altolat, Bis(6-Dimethylamino-2-(2-(2,5-Dimethyl-1-Phenylpyrrol-3-Yl)Vinyl)-1-Methylquinolinium) 3,3-Dihydroxy-4,4-Methylenedi-2-Naphthoate, Bis[6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methylquinolinium] 4,4′-methylenebis[3-hydroxy-2-naphthoate], Molevac, NSC 223622, Neo-Oxypaat, Pamovin, Poquil, Povan, Povanil, Povanyl, Pyrcon, Pyrvinium Embonate, Quinolinium, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-, 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylate] (2:1), Quinolinium, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-, salt with 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylic acid] (2:1), Quinolinium, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methyl-, salt with 4,4′-methylenebis[3-hydroxy-2-naphthoic acid] (2:1), Tolapin, Vanquin, Vermitibier, Viprynium Embonate, bis{6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methylquinolinium} 4,4'-methanediylbis(3-hydroxynaphthalene-2-carboxylate)
• CAS: 3546-41-6

Description

Pyrvinium pamoate is an anthelmintic drug that is used to treat parasitic worm infections. It has been shown to have potent antitumor activity and has been used in the treatment of a variety of cancers, including breast cancer. Pyrvinium pamoate can inhibit tumor cell viability by interfering with energy metabolism and mitochondrial membrane potential. It also inhibits the production of growth factor-β1, which is involved in carcinogenesis. This drug has been shown to cause cellular necrosis, apoptosis, and autophagy in experimental models. Pyrvinium pamoate can be used as a pharmacokinetic probe for studying drug transport across the blood-brain barrier.

• Brand: Biosynth

Chemical properties

• Molecular weight: 1,151.39 g/mol
• Formula: (C₂₆H₂₈N₃)₂•C₂₃H₁₄O₆
• Purity: Min. 95%
• Color/Form: Powder