5-(2-Aminoethyl)benzene-1,2,4-triol hydrochloride
CAS: 28094-15-7
Ref. 3D-DBA09415
| 5mg | 136.00 € | ||
| 10mg | 192.00 € | ||
| 25mg | 271.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 544.00 € |
Product Information
- 1,2,3-Benzenetriol, 4-(2-aminoethyl)-, hydrochloride
- 1,2,4-Benzenetriol, 5-(2-aminoethyl)-, hydrochloride
- 1,2,4-Benzenetriol, 5-(2-aminoethyl)-, hydrochloride (1:1)
- 2,4,5-Trihydroxyphenethylamine hydrochloride
- 4-(2-Aminoethyl)-1,2,3-benzenetriol hydrochloride
- 5-(2-Aminoethyl)-1,2,4-benzenetriol hydrochloride
- 5-(2-Aminoethyl)Benzene-1,2,4-Triol Hydrochloride (1:1)
- 6-Hydroxydopamine chloride
- 6-Hydroxydopamine hydrochloride
- Nsc 233898
- See more synonyms
- Oxidopamine HCl
- Oxidopamine hydrochloride
5-(2-Aminoethyl)benzene-1,2,4-triol hydrochloride (MPP+) is a neurotoxin that inhibits the synthesis of dopamine and other neurotransmitters in dopaminergic neurons. MPP+ is generated by the oxidation of l-dopa, an amino acid precursor of the neurotransmitter dopamine. MPP+ causes oxidative injury to dopaminergic neurons by affecting their mitochondria. The inhibition of mitochondrial function leads to neuronal death and Parkinson's disease. MPP+ has been shown to be cytotoxic for pluripotent cells, such as embryonic stem cells, which are important for regenerative medicine. In addition, MPP+ has been shown to cause lesions in the brain and induce cell death in a model system using rat striatum neurons and astrocytes. This agent also inhibits polymerase chain reaction (PCR), which can be used as a diagnostic tool for Parkinson's disease.
Chemical properties
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