2,6-Diiodophenol
CAS: 28177-54-0
Ref. 3D-DBA17754
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire | ||
| 250mg | To inquire |
Product Information
2,6-Diiodophenol is a noncompetitive inhibitor that binds to the active site of carbonic anhydrase. It can be used as a pharmaceutical formulation or in sample preparation for gene sequence analysis. 2,6-Diiodophenol has been shown to have competitive inhibition against other inhibitors such as acetazolamide and dichlorphenamide. The marine sponge-derived enzyme carbonic anhydrase (CA) from the Gulf of Mexico was examined by chromatographic and spectroscopic methods. The CA activity was found to be inhibited by 2,6-diiodophenol in a concentration dependent manner with a KI value of 0.06 mM. 2,6-Diiodophenol also inhibits CA activity in rat liver microsomes at concentrations above 1 mM but does not inhibit peroxide production by the microsomal system at concentrations up to 10 mM. The crystal structure of 2,6-diiodophenol bound to CA has been determined using X
Chemical properties
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