Ditekiren

CAS: 103336-05-6

Ref. 3D-DEA33605

Product Information

• Name: Ditekiren
• Synonyms: Ditekiren [USAN:INN], Ditekirene, Ditekirene [INN-French], Ditekirenum, Ditekirenum [INN-Latin], Ditiquireno, Ditiquireno [INN-Spanish], L-Histidinamide, 1-((1,1-dimethylethoxy)carbonyl)-L-prolyl-L-phenylalanyl-N-(2-hydroxy-5-methyl-1-(2-methylpropyl)-4-(((2-methyl-1-(((2-pyridinylmethyl)amino)carbonyl)butyl)amino)carbonyl)hexyl)-N(sup alpha)-methyl-, (1S-(1R*,2R*,4R*(1R*,2R*)))-, tert-Butyl (2S)-2-(((alphaS)-alpha-(((1S)-1-(((1S,2S,4S)-2-hydroxy-1-isobutyl-5-methyl-4-(((1S,2S)-2-methyl-1-((2-pyridylmethyl)carbamoyl)butyl)carbamoyl)hexyl)carbamoyl)-2-imidazol-4-ylethyl)methylcarbamoyl)phenethyl)carbamoyl)-1-pyrrolidinecarboxylate, L-Histidinamide, 1-((1,1-dimethylethoxy)carbonyl)-L-prolyl-L-phenylalanyl-N-(2-hydroxy-5-methyl-1-(2-methylpropyl)-4-(((2-methyl-1-(((2-pyridinylemthyl)amino)carbonyl)butyl)amino)carbonyl)hexyl)-Nalpha-methyl-, (1S-(1R*,2R*,4R*(1R*,2R*)))-, 1-(tert-butoxycarbonyl)-L-prolyl-L-phenylalanyl-N-[(1S,2S,4S)-2-hydroxy-5-methyl-1-(2-methylpropyl)-4-({(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)carbamoyl]butyl}carbamoyl)hexyl]-Nα-methyl-L-histidinamide

Description

Ditekiren is an enzyme inhibitor that blocks fatty acid uptake and transport in the intestine. The chemical structure of ditekiren is a glycopeptide that inhibits dipeptidyl peptidase IV (DPP-IV) in vitro. Ditekiren has been used clinically for the treatment of coronary heart diseases, with a recent study showing it to be effective against congestive heart failure. Ditekiren also inhibits organic anion transporters and acidic phospholipids, which may contribute to its therapeutic effects.

• Brand: Biosynth

Chemical properties

• Molecular weight: 930.2 g/mol
• Formula: C₅₀H₇₅N₉O₈
• Purity: Min. 95%