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N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
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N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

CAS: 253168-86-4

Ref. 3D-DKA16886

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Estimated delivery in United States, on Wednesday 8 Jan 2025

Product Information

Name:
N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
Description:

Apremilast is a prodrug that is converted in vivo to its active form. It inhibits the production of tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), which are inflammatory cytokines. Apremilast is also an inhibitor of phosphodiesterase 4 (PDE4), which degrades cyclic adenosine monophosphate (cAMP). This drug has been shown to be effective in the treatment of arthritis, with pain relief after two weeks and improvement in joint mobility after four weeks. Apremilast is available as a racemate, with enantiomers having different pharmacological properties. The most potent form of apremilast is the S(-) enantiomer, which has been shown to be more potent than the R(+) enantiomer for inhibition of TNF-α and IL-1β.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
460.5 g/mol
Formula:
C22H24N2O7S
Purity:
Min. 95%
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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