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PF-04418948
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PF-04418948

CAS: 1078166-57-0

Ref. 3D-DTB16657

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Estimated delivery in United States, on Tuesday 2 Jul 2024

Product Information

Name:
PF-04418948
Synonyms:
  • Pf 04418948
  • 1-(4-Fluorobenzoyl)-3-[(6-Methoxynaphthalen-2-Yl)Oxymethyl]Azetidine-3-Carboxylic Acid
Description:

PF-04418948 is a potent and selective antagonist of the camp receptor. It inhibits the binding of camp to the receptor, thereby inhibiting activation of downstream signaling pathways. PF-04418948 has been shown to inhibit cyclase activity in vitro, which may account for its effects on PGE2 levels. PF-04418948 also prevents cytosolic Ca2+ accumulation by blocking cation channels, which may contribute to its neuroprotective effects. PF-04418948 has been shown to have anti-angiogenic properties in vivo and in vitro experiments. This drug also blocks glutamate release from activated microglia and toll-like receptor signaling pathways, thereby suppressing microbial infection.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
409.41 g/mol
Formula:
C23H20FNO5
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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