PD146176

CAS: 4079-26-9

Ref. 3D-EAA07926

Product Information

• Name: PD146176
• Synonyms: [1]Benzothiopyrano[4,3-b]indole, 6,11-dihydro-, 6,11-Dihydro-5-Thia-11-Aza-Benzo(A)-Fluorene
• CAS: 4079-26-9

Description

PD146176 is a potential anti-cancer compound that inhibits the tumor necrosis factor (TNF) receptor. PD146176 is a small molecule inhibitor of TNF signaling and has been shown to reduce atherosclerotic lesion size in mice. The drug also protects against neuronal death induced by an inflammatory stimulus, such as toll-like receptor 4 (TLR4) agonists. It has been demonstrated to have synergistic activity with other compounds in experiments using miapaca-2 cells and has been shown to inhibit cancer cell growth in culture and in an experimental model. PD146176 may be a target for the development of new drugs for the treatment of various diseases, including bowel disease and cancer.

• Brand: Biosynth

Chemical properties

• Molecular weight: 237.32 g/mol
• Formula: C₁₅H₁₁NS
• Purity: Min. 95%