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JNJ-42153605
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JNJ-42153605

CAS: 1254977-87-1

Ref. 3D-EAC97787

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Estimated delivery in United States, on Monday 30 Dec 2024

Product Information

Name:
JNJ-42153605
Description:

JNJ-42153605 is a novel allosteric modulator of the NMDA receptor. It is an agonist at the MGLUR2 receptor and has been shown to have a long-term treatment effect in animal models. JNJ-42153605 has also been shown to be effective in clinical trials for the treatment of patients with major depressive disorder and schizophrenia. The onset latency of this drug is less than one hour and its effects last up to 24 hours. This drug binds to glutamate receptors, which are ionotropic receptors that mediate fast synaptic transmission. JNJ-42153605 acts as an allosteric modulator by binding to a site that is different from the agonist binding site, but near it. The binding of JNJ-42153605 at this site increases the affinity of glutamate for its receptor, leading to increased uptake and activation of ion channels. This leads to excitatory postsynaptic potentials (EPSPs) and

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
400.44 g/mol
Formula:
C22H23F3N4
Purity:
Min. 95%
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Hazard Info

UN Number:
EQ:
Class:
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Forbidden to fly:
Hazard Info:
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LQ:

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