N-(4-Aminophenyl)maleimide

CAS: 29753-26-2

Ref. 3D-EBA75326

Product Information

• Name: N-(4-Aminophenyl)maleimide
• Synonyms: (p-Aminophenyl)maleimide, 1-(4-Aminophenyl)-1H-pyrrole-2,5-dione, 1-(4-Aminophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione, 1-(4-Aminophenyl)pyrrole-2,5-dione, 1H-Pyrrole-2,5-dione, 1-(4-aminophenyl)-, N-(p-Aminophenyl)maleimide

Description

N-(4-Aminophenyl)maleimide is a bifunctional chemical that reacts with the sulfhydryl groups in proteins. It is used as a model system to study the mechanism of action of alkylating agents and their effect on biological systems. N-(4-Aminophenyl)maleimide reacts with disulphides and paraformaldehyde, which are commonly found in tissues, to form fluorescent endpoints. This reaction can be detected by staining sections of tissue with diaminobenzidine and examining under ultraviolet light or by using an electron microscope. The organomercurials methyl mercury chloride and dimethyl mercury chloride can be reduced catalytically by N-(4-aminophenyl)maleimide to form the corresponding mercaptides. Chemical analyses have shown that this reaction is reversible, forming N-(4-aminophenyl)maleimide as a product.

• Brand: Biosynth

Chemical properties

• Molecular weight: 188.19 g/mol
• Formula: C₁₀H₈N₂O₂
• Purity: Min. 95%