TPI-1
CAS: 79756-69-7
Ref. 3D-EDA75669
1g | Discontinued | ||
2g | Discontinued | ||
5g | Discontinued | ||
5mg | Discontinued | ||
10mg | Discontinued | ||
25mg | Discontinued | ||
50mg | Discontinued | ||
100mg | Discontinued | ||
250mg | Discontinued | ||
500mg | Discontinued |
Product Information
TPI-1 is a HDAC inhibitor that has shown to have an apoptotic effect on cancer cells. It inhibits the production of reactive oxygen species, leading to cell death. TPI-1 may inhibit gene transcription by binding to the protein phosphatase and inhibiting its activity. TPI-1 has been shown to have a primary tumor growth inhibitory effect in mouse models of breast cancer and cervical cancer. TPI-1 induces apoptosis in human cervical cancer cells. It also induces apoptosis in rat primary tumors implanted subcutaneously in athymic mice, with no observed toxicity.