Product Information
- 3,4-dihydro-5-methyl-1(2H)-isoquinolinone
- 5-methyl-3,4-dihydroisoquinolin-1(2H)-one
- Pd-128763
5-Methyl-3,4-dihydroisoquinolin-1(2H)-one is a detectable compound that is found in adventitia. It has been shown to have polymerase activity and can be used to inhibit restenosis following angioplasty. 5-Methyl-3,4-dihydroisoquinolin-1(2H)-one inhibits the proliferation of vascular smooth muscle cells by inhibiting the synthesis of phosphoenolpyruvate, which is an important substrate for cellular respiration. This drug also inhibits cellular proliferation and neointimal hyperplasia in a hepatoma cell line. The drug has been shown to be effective at reducing neointimal hyperplasia following angioplasty in a porcine model of vascular injury.
Chemical properties
Technical inquiry about: 3D-EFA07556 5-Methyl-3,4-dihydroisoquinolin-1(2H)-one
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