Naphthol AS-BI N-acetyl-b-D-glucosaminide
CAS: 3395-37-7
Ref. 3D-EN06141
| 25mg | 175.00 € | ||
| 50mg | 237.00 € | ||
| 100mg | 371.00 € | ||
| 250mg | 660.00 € | ||
| 500mg | 943.00 € |
Product Information
- 2-Naphth-o-anisidide, 3-[(2-acetamido-2-deoxy-β-<span class="text-smallcaps">D</span>-glucopyranosyl)oxy]-7-bromo-
- 2-Naphthalenecarboxamide, 3-[[2-(acetylamino)-2-deoxy-β-<span class="text-smallcaps">D</span>-glucopyranosyl]oxy]-7-bromo-N-(2-methoxyphenyl)-
- 3-[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-7-bromo-N-(2-methoxyphenyl)naphthalene-2-carboxamide
- 3-[[2-(Acetylamino)-2-deoxy-β-<span class="text-smallcaps">D</span>-glucopyranosyl]oxy]-7-bromo-N-(2-methoxyphenyl)-2-naphthalenecarboxamide
- Glucopyranoside, 6-bromo-3-[(o-methoxyphenyl)carbamoyl]-2-naphthyl 2-acetamido-2-deoxy-+, β-<span class="text-smallcaps">D</span>-
Naphthol AS-BI N-acetyl-b-D-glucosaminide is an enzyme inhibitor that is used in the treatment of Gaucher's disease. The enzyme it inhibits is β-glucosidase, which breaks down glucocerebrosides in the lysosomes of cells. This drug prevents the breakdown of glucocerebrosides and increases their concentration in cells, which reduces the symptoms of Gaucher's disease. Naphthol AS-BI N-acetyl-b-D-glucosaminide has been shown to be effective against wild type and mutant forms of the enzyme. However, it does not work against patients who are homozygous for a mutation in exon 1 of the βglu gene that codes for βglu protein.
Chemical properties
Technical inquiry about: 3D-EN06141 Naphthol AS-BI N-acetyl-b-D-glucosaminide
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