1,3-Acetonedicarboxylic acid

CAS: 542-05-2

Ref. 3D-FA00389

Product Information

• Name: 1,3-Acetonedicarboxylic acid
• Synonyms: 3-Oxoglutaric acid, 1,3-Acetone diacrboxylic acid, 1,3-Dicarboxyacetone, 3-Ketoglutaric acid, 3-Oxopentanedioate, 3-Oxopentanedioic acid, Acetone-1,3-dicarboxylic acid, Glutaric acid, 3-oxo-, Glutaric acid, β-oxo-, Pentanedioic acid, 3-oxo-, s-Acetonedicarboxylic acid, β-Ketoglutaric acid, β-Oxoglutaric acid
• CAS: 542-05-2

Description

1,3-Acetonedicarboxylic acid is a crystalline solid that belongs to the group of carboxylic acids. 1,3-Acetonedicarboxylic acid interacts with its receptor by binding to a hydroxyl group and two hydrogen atoms. It has been shown that 1,3-acetonedicarboxylic acid can inhibit HIV infection in vitro by preventing the virus from attaching to cells. It also inhibits malonic acid oxidation and citric acid cycle enzymes in rat liver mitochondria. The synthesis of 1,3-acetonedicarboxylic acid can be achieved through different methods:

1) By reacting sodium carbonate with malonic acid
2) By reacting hydrogen fluoride with malonic acid
3) By reacting sodium carbonate with citric acid (malonic ester) and then hydrolyzing it
4) By reacting sodium carbonate with malonitrile and then hydro

• Brand: Biosynth

Chemical properties

• Molecular weight: 146.1 g/mol
• Formula: C₅H₆O₅
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C5H6O5/c6-3(1-4(7)8)2-5(9)10/h1-2H2,(H,7,8)(H,9,10)
• InChI key: InChIKey=OXTNCQMOKLOUAM-UHFFFAOYSA-N
• SMILES: O=C(O)CC(=O)CC(=O)O