2-Amino-6-chloropurine

CAS: 10310-21-1

Ref. 3D-FA02581

Product Information

• Name: 2-Amino-6-chloropurine
• Synonyms: 6-Chloroguanine, 1H-Purin-2-amine, 6-chloro-, 2-Amino-6-chloro-9H-purine, 2-Amino-6-chloro-purine, 6-Chloro-1H-purin-2-amine, 6-Chloro-2-aminopurine, 6-Chloro-2-purinamine, 6-Chloro-9H-purin-2-amine, 6-Chloro-9H-purin-2-yl-2-amine, 6-Chloroguanine Crystalline, 6-chloro-5H-purin-2-amine, 6-chloro-7H-purin-2-amine, 6-chloro-7H-purin-2-ylamine, 9H-Purin-2-amine, 6-chloro-, NSC 29570, Purine, 2-amino-6-chloro-
• CAS: 10310-21-1

Description

2-Amino-6-chloropurine is a nucleophilic substituent that is used in the synthesis of 2-amino-6-chloropurine. It reacts with hydroxyl groups to form a palladium-catalyzed coupling reaction solution, which is then treated with hydrochloric acid and trifluoroacetic acid. The product is purified by crystallization and recrystallization. This compound has potent antitumor activity against carcinoma cell lines, but it has not been shown to have any effect against Mycobacterium tuberculosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 169.57 g/mol
• Formula: C₅H₄ClN₅
• Purity: Min. 95%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C5H4ClN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11)
• InChI key: InChIKey=RYYIULNRIVUMTQ-UHFFFAOYSA-N
• SMILES: Nc1nc(Cl)c2[nH]cnc2n1