2-Aminoisobutyric acid

CAS: 62-57-7

Ref. 3D-FA02753

Product Information

• Name: 2-Aminoisobutyric acid
• Synonyms: a-Amino isobutyric acid, 2,2-Dimethylglycine, 2-Amino-2-methylpropanoic acid, 2-Amino-2-methylpropionic acid, 2-Amino-2-methylpropionsaure, 2-Methylalanine, AIB, Acide 2-amino-2-methylpropionique, Acido 2-Amino-2-Metilpropionico, Alanine, 2-methyl-, Aminoisobutyric acid, H-Aib-OH, Nsc 16590, alpha-Aminoisobutyric acid, Α-Aminoisobutyric Acid, α,α-Dimethylglycine, α-Aminoisobutanoic acid, α-Methylalanine

Description

2-Aminoisobutyric acid (2-AIBA) is a natural compound that has been shown to have significant cytotoxicity against cancer cells. It is also thermodynamically stable and has a low toxicity in normal cells. 2-AIBA is able to cross the blood-brain barrier and can be taken up by the trigeminal nerve. It has been found to have lactogenic effects on the mammary gland, which may be due to its ability to increase prolactin levels. 2-AIBA has been shown to significantly inhibit radiation induced apoptosis in a model system of human papillary muscle cells. The uptake of 2-AIBA was found to be dependent on its ester hydrochloride form, with titration calorimetry being used for this study.

• Brand: Biosynth

Chemical properties

• Molecular weight: 103.12 g/mol
• Formula: C₄H₉NO₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)
• InChI key: InChIKey=FUOOLUPWFVMBKG-UHFFFAOYSA-N
• SMILES: CC(C)(N)C(=O)O