2-Amino-1,3,4-thiadiazole

CAS: 4005-51-0

Ref. 3D-FA03993

Product Information

• Name: 2-Amino-1,3,4-thiadiazole
• Synonyms: 1,3,4-Thiadiazol-2-amine, 1,3,4-Thiadiazol-2-ylamine, 1,3,4-Thiadiazole, 2-amino-, 1,3,4-Thiadiazole-2-amine, 2-Amine-1,3,4-thiadiazole, 2-Amino-1,3,4-Thiodiazole, 2-Aminothiadiazole, 5-Amino-1,3,4-thiadiazole, Amino-1,3,4-thiadiazole,2-, Aminothiadiazole, NSC 4728, Tf 128
• CAS: 4005-51-0

Description

2-Amino-1,3,4-thiadiazole is a metabolic inhibitor that binds to the ryanodine receptor, a calcium channel in the sarcoplasmic reticulum of muscle cells. This drug has potent antitumor activity and is used to treat metastatic colorectal cancer. 2-Amino-1,3,4-thiadiazole also inhibits microbial growth by binding to the dinucleotide phosphate (NAD) coenzyme complex and preventing bacterial metabolism. It may be an effective antimicrobial agent against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pneumoniae. The nitrogen atoms in 2-amino-1,3,4-thiadiazole bind to chloride ions and form thiazolidine derivatives with malonic acid as a noncompetitive inhibitor of ATP synthesis. In addition, this drug inhibits protein synthesis by binding to the 30S rib

• Brand: Biosynth

Chemical properties

• Molecular weight: 101.13 g/mol
• Purity: Min. 95%
• Color/Form: White/Off-White Solid