6-Amino-1-benzyluracil

CAS: 41862-11-7

Ref. 3D-FA04268

Product Information

• Name: 6-Amino-1-benzyluracil
• Synonyms: 2(1H)-pyrimidinone, 6-amino-4-hydroxy-1-(phenylmethyl)-, 2,4(1H,3H)-pyrimidinedione, 6-amino-1-(phenylmethyl)-, 6-Amino-1-(phenylmethyl)-2,4(1H,3H)-pyrimidinedione, 6-Amino-1-Benzyl-1,2,3,4-Tetrahydropyrimidine-2,4-Dione, 6-Amino-1-benzyl-1,3-dihydropyrimidine-2,4-dione, NSC 70496

Description

6-Amino-1-benzyluracil is a triethyl orthoformate that reacts with an aldehyde to form an imine. This reaction is known as alkylation. The imine reacts with benzamidine to form an anticancer drug called lumazine, which has been shown to be effective against cancer cells. 6-Amino-1-benzyluracil had low solubility in water and was therefore refluxed with ethyl acetoacetate and elemental acetoacetate. 6-Amino-1-benzyluracil is insoluble in the organic phase and can be removed by filtration.

• Brand: Biosynth

Chemical properties

• Molecular weight: 217.22 g/mol
• Formula: C₁₁H₁₁N₃O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H11N3O2/c12-9-6-10(15)13-11(16)14(9)7-8-4-2-1-3-5-8/h1-6H,7,12H2,(H,13,15,16)
• InChI key: InChIKey=QMKJOZVQZBJSEC-UHFFFAOYSA-N
• SMILES: Nc1cc(=O)[nH]c(=O)n1Cc1ccccc1