N2-Acetyl-O6-diphenylcarbamoylguanine

CAS: 112233-74-6

Ref. 3D-FA08314

Product Information

• Name: N2-Acetyl-O6-diphenylcarbamoylguanine

Description

N2-Acetyl-O6-diphenylcarbamoylguanine is an amide nucleoside that is a potent antiviral agent. It inhibits the synthesis of viral DNA by inhibiting viral DNA polymerase. N2-Acetyl-O6-diphenylcarbamoylguanine also has reactive functional groups that can react with other molecules, such as human serum albumin, to form conjugates that are more stable and can be used for long periods of time. This nucleoside is synthesized by reacting uridine with chloroacetamide and then reacting the resulting product with diphenylcarbamoyl chloride in the presence of triethylamine. The ring opening reaction leads to the formation of a glycosidic linkage between N2-Acetyl-O6-diphenylcarbamoylguanine and the sugar molecule. This nucleoside has been shown to

• Brand: Biosynth

Chemical properties

• Molecular weight: 388.38 g/mol
• Formula: C₂₀H₁₆N₆O₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C20H16N6O3/c1-13(27)23-19-24-17-16(21-12-22-17)18(25-19)29-20(28)26(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-12H,1H3,(H2,21,22,23,24,25,27)
• InChI key: InChIKey=YWKXGPPEBHDNGM-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1nc(OC(=O)N(c2ccccc2)c2ccccc2)c2[nH]cnc2n1