4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
CAS: 914471-09-3
Ref. 3D-FA100805
5mg | Discontinued | ||
10mg | Discontinued | ||
25mg | Discontinued |
Product Information
Epacadostat is a drug that inhibits the protein kinase, Janus-activated kinase 2 (JAK2), and thus blocks the production of cytokines. Epacadostat has been shown to be effective in inhibiting tumor growth in mice with cancer. Epacadostat also binds to the toll-like receptor 9 (TLR9) and is being studied for its potential use in treating infectious diseases. Epacadostat has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.