![4-Amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)-2-cyclopenten-1-yl]-2(1H)-pyrimidinone](https://static.cymitquimica.com/products/3D/img/FA102543.png "Click to enlarge")
4-Amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)-2-cyclopenten-1-yl]-2(1H)-pyrimidinone
CAS: 865838-26-2
Ref. 3D-FA102543
| 1mg | To inquire | |
| 5mg | To inquire | |
| 10mg | To inquire |
Product Information
4-Amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)-2-cyclopenten-1-yl]-2(1H)-pyrimidinone (4AP) is a potent inhibitor of methyltransferase enzymes. It is currently being researched as a potential treatment for metastatic pancreatic cancer. 4AP binds to the active site of the enzyme and prevents it from transferring methyl groups onto DNA. This prevents cell proliferation and tumor growth by inhibiting RNA and protein synthesis. 4AP also has anticancer activity against mouse tumors in vitro. 4AP has been shown to be an effective inhibitor of myeloid-derived suppressor cells (MDSCs). MDSCs are immune cells that have been shown to have a negative effect on tumor growth. The mechanism of action is not yet fully understood but it is thought that this may be due to the
Chemical properties
Technical inquiry about: 3D-FA102543 4-Amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)-2-cyclopenten-1-yl]-2(1H)-pyrimidinone
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
