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[(2R,3S,5R)-2-(Acetyloxymethyl)-5-[5-Fluoro-3-(3-Methylbenzoyl)-2,4-Dioxopyrimidin-1-Yl]Oxolan-3-Yl] Acetate
CAS: 74596-17-1
Ref. 3D-FA102889
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Product Information
- Uridine, 2'-deoxy-5-fluoro-3-(3-methylbenzoyl)-, 3',5'-diacetate
[(2R,3S,5R)-2-(Acetyloxymethyl)-5-[5-Fluoro-3-(3-Methylbenzoyl)-2,4-Dioxopyrimidin-1-Yl]Oxolan-3-Yl] Acetate is a prodrug that has been shown to be effective against cancer cells in vitro and in vivo. It is converted by deacetylation into the active form of the drug, [(2R,3S,5R)-2-(Acetyloxymethyl)-5-[5-Fluoro-3-(3-Methylbenzoyl)-2,4-Dioxopyrimidin-1-Yl]Oxolan]-3-Yl] Acetic Acid (TZPPA), which inhibits thymidine synthesis. TZPPA has been shown to be more potent than peplomycin for the treatment of muc
Chemical properties
Technical inquiry about: 3D-FA102889 [(2R,3S,5R)-2-(Acetyloxymethyl)-5-[5-Fluoro-3-(3-Methylbenzoyl)-2,4-Dioxopyrimidin-1-Yl]Oxolan-3-Yl] Acetate
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