AG 13958

CAS: 319460-94-1

Ref. 3D-FA103515

Product Information

• Name: AG 13958
• CAS: 319460-94-1

Description

AG 13958 is a biological product that is used to treat age-related macular degeneration. It is an anti-VEGF (vascular endothelial growth factor) agent that inhibits the production of VEGF by binding to the VEGFR2 protein, thereby preventing the development of new blood vessels in the retina. AG 13958 has an effective dose range from 0.1 mg/kg to 1 mg/kg, with a maximum tolerated dose of 2 mg/kg. The most common adverse effect is vein occlusion. This drug has been shown to be a viable treatment for eye disorders such as retinal tissue damage and diseases such as cancer and other eye disorders. AG 13958 binds to tyrosine kinase receptors on cells and stimulates cell growth, which may be useful for treating cancer or other eye disorders.

• Brand: Biosynth

Chemical properties

• Molecular weight: 467.5 g/mol
• Formula: C₂₆H₂₂FN₇O
• Purity: Min. 95%
• InChI: InChI=1S/C26H22FN7O/c1-16-13-25(34(2)33-16)26(35)30-24-15-19(7-10-21(24)27)29-18-6-9-20-22(31-32-23(20)14-18)11-8-17-5-3-4-12-28-17/h3-15,29H,1-2H3,(H,30,35)(H,31,32)/b11-8+
• InChI key: InChIKey=JXSVVZKPEDIRTN-DHZHZOJOSA-N
• SMILES: Cc1cc(C(=O)Nc2cc(Nc3ccc4c(/C=C/c5ccccn5)n[nH]c4c3)ccc2F)n(C)n1