H-Arg-Glu-OH

CAS: 15706-89-5

Ref. 3D-FA107983

Product Information

• Name: H-Arg-Glu-OH
• Synonyms: 1738: PN: WO2007124090 PAGE: 84 claimed protein, 23: PN: WO2021055880 SEQID: 24 claimed protein, 410: PN: EP2071334 SEQID: 441 claimed protein, 410: PN: WO2009077864 SEQID: 441 claimed protein, <span class="text-smallcaps">L</smallcap>-Arginyl-<smallcap>L</span>-glutamic acid, <span class="text-smallcaps">L</smallcap>-Glutamic acid, <smallcap>L</span>-arginyl-, <span class="text-smallcaps">L</smallcap>-Glutamic acid, N-<smallcap>L</span>-arginyl-, Glutamic acid, N-arginyl-, NSC 186916, N~5~-(diaminomethylidene)ornithylglutamic acid
• CAS: 15706-89-5

Description

H-Arg-Glu-OH is a small molecule that is used as a pharmacological agent for the treatment of diabetes. It has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit the production of inflammatory mediators such as prostaglandin E2 and nitric oxide. H-Arg-Glu-OH also induces apoptosis in human monocytes and macrophages by binding to toll-like receptor 4 (TLR4) on the cell surface. This binding activates NFκB and JNK pathways, leading to the induction of apoptosis. H-Arg-Glu-OH binds with high affinity to monoclonal antibodies against glutamic acid and glycine, which are not present in humans. The compound may be toxic at a neutral pH because it is highly reactive due to intramolecular hydrogen bonding between carbonyl oxygens and amide hydrogens.

• Brand: Biosynth

Chemical properties

• Molecular weight: 303.32 g/mol
• Formula: C₁₁H₂₁N₅O₅
• Purity: Min. 95%