Ac-Tyr-Val-Ala-Asp-2,6-dimethylbenzoyloxymethylketone
CAS: 154674-81-4
Ref. 3D-FA111062
| 2mg | 298.00 € | ||
| 5mg | 495.00 € | ||
| 10mg | 820.00 € | ||
| 25mg | 1,543.00 € | ||
| 50mg | 2,684.00 € |
Product Information
- Ac-YVAD-2,6-dimethylbenzoyloxymethylketone
- Ac-YVAD-AOM
- Ac-Yvad-2,6-Dimethylbenzoyloxymethylketone
Ac-Tyr-Val-Ala-Asp-2,6-dimethylbenzoyloxymethylketone is a potent transcriptional regulator that can be used to treat breast cancer. Ac-Tyr-Val-Ala-Asp-2,6-dimethylbenzoyloxymethylketone binds to estrogen receptor and prevents the binding of estrogen to its receptor. This leads to the death of cancer cells by inhibiting the function of bcl family proteins. Acetylation of this compound at C8, C10, and C17 positions increases its potency in vivo. In addition, Acetylated TAVADM can inhibit pancreatic cancer cell growth by activating signal transducer and activator of transcription 3 (STAT3) and inhibiting the activity of bcl family proteins such as BCL2 and BCLXL. Acetylated TAVADM has also been shown to have antiapoptotic
Chemical properties
Technical inquiry about: 3D-FA111062 Ac-Tyr-Val-Ala-Asp-2,6-dimethylbenzoyloxymethylketone
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