Ac-Val-OMe

CAS: 1492-15-5

Ref. 3D-FA111817

Product Information

• Name: Ac-Val-OMe

Description

Ac-Val-OMe is a trimethyl l-amino acid that is found in nature. It has been shown to be an inhibitor of serine protease, including cathepsin K and thrombin, as well as other enzymes. Ac-Val-OMe has been shown to have a catalytic rate of 1.5 x 10^6 M/s at pH 7 and a residue specific activity of 2.8 x 10^4 U/mg at pH 6. Ac-Val-OMe also inhibits the activity of n-acetyl-l-tyrosine amidohydrolase which is involved in the biosynthesis of tyrosine, histidine and tryptophan. The stereospecificity of this compound was determined using L-(+)-serine and D-(−)-serine as substrates with the enzyme chymotrypsin. The product ratio was 3:1 when Ac-Val-OMe was used

• Brand: Biosynth

Chemical properties

• Molecular weight: 173.21 g/mol
• Formula: C₈H₁₅NO₃
• Purity: Min. 95%
• InChI: InChI=1S/C8H15NO3/c1-5(2)7(8(11)12-4)9-6(3)10/h5,7H,1-4H3,(H,9,10)/t7-/m0/s1
• InChI key: InChIKey=KCHNPFJMSOGXIT-ZETCQYMHSA-N
• SMILES: COC(=O)[C@@H](NC(C)=O)C(C)C