N-(3-Acetylphenyl)benzamide

CAS: 84833-25-0

Ref. 3D-FA114496

Product Information

• Name: N-(3-Acetylphenyl)benzamide

Description

3-Acetylphenylbenzamide (APB) is a potent and selective HIV integrase inhibitor that inhibits the catalytic activity of HIV integrase. It has been shown to inhibit the replication of HIV-1 in human cells, including primary CD4+ T cells, by blocking the integration of viral DNA into the host genome. APB is structurally related to diketoacids, which are inhibitors of cellular protein synthesis, and can be used as a lead compound for developing therapeutics against HIV-1. The chemical structure of APB has been validated using nuclear magnetic resonance spectroscopy.

• Brand: Biosynth

Chemical properties

• Molecular weight: 239.27 g/mol
• Formula: C₁₅H₁₃NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C15H13NO2/c1-11(17)13-8-5-9-14(10-13)16-15(18)12-6-3-2-4-7-12/h2-10H,1H3,(H,16,18)
• InChI key: InChIKey=WLMCJZXPENYTMD-UHFFFAOYSA-N
• SMILES: CC(=O)c1cccc(NC(=O)c2ccccc2)c1