4-(1-Adamantyl)benzenesulfonyl chloride
CAS: 144174-50-5
Ref. 3D-FA117188
1g | 1,350.00 € | ||
100mg | 364.00 € | ||
250mg | 541.00 € | ||
500mg | 854.00 € |
Product Information
4-Adamantylbenzenesulfonyl chloride is a conformationally constrained analogue of the natural product 1,2-dihydrobenzofuran. It is a potent inhibitor of human cytochrome P450 enzymes, with Ki values in the range of 2 to 10 nM. 4-Adamantylbenzenesulfonyl chloride binds to the active site of cytochrome P450 and blocks access to substrate, thereby inhibiting the metabolism of drugs such as phenytoin and propranolol. 4-Adamantylbenzenesulfonyl chloride can be used as a probe for investigating enzyme activity in vitro or in vivo.
Chemical properties
Technical inquiry about: 3D-FA117188 4-(1-Adamantyl)benzenesulfonyl chloride
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