N-(4-Acetylphenyl)-2-bromoacetamide

CAS: 29182-93-2

Ref. 3D-FA120415

Product Information

• Name: N-(4-Acetylphenyl)-2-bromoacetamide
• Synonyms: acetamide, N-(4-acetylphenyl)-2-bromo-

Description

N-(4-Acetylphenyl)-2-bromoacetamide (NAP-2BA) is a hybridized compound that inhibits the activity of cytochrome P450 isozymes and Bcl-2 proteins. It has been shown to have significant anti-inflammatory properties and has been studied for its anti-cancer potential in pancreatic cancer cells. NAP-2BA interacts with the Cox-1 enzyme, which is involved in the metabolism of coxibs and NSAIDs. NAP-2BA also has a strong effect on cell growth inhibition and apoptosis induction, which may be due to its ability to inhibit cyclin D1 synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 256.1 g/mol
• Formula: C₁₀H₁₀BrNO₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H10BrNO2/c1-7(13)8-2-4-9(5-3-8)12-10(14)6-11/h2-5H,6H2,1H3,(H,12,14)
• InChI key: InChIKey=VXYNUOWJSXXSRR-UHFFFAOYSA-N
• SMILES: CC(=O)c1ccc(NC(=O)CBr)cc1