4-Amino-N-pyrimidin-2-ylbenzenesulfonamide

CAS: 116-44-9

Ref. 3D-FA123939

Product Information

• Name: 4-Amino-N-pyrimidin-2-ylbenzenesulfonamide
• Synonyms: benzenesulfonamide, 4-amino-N-2-pyrimidinylSulfazinum, Adiazin, Debenal, Pirimal, Pyrimal, Sulfadiazin, Sulfapyrazine, 116-44-9, 2-Sulfanilamidopyrazine, 4-Amino-N-(pyrazinyl)benzenesulfonamide, 4-Amino-N-2-pyrazinylbenzenesulfonamide, Benzenesulfonamide, 4-amino-N-pyrazinyl-, N¹-2-Pyrazinylsulfanilamide, NSC 25872, NSC 41835, Pyrazine, sulfanilamido-, Sulfanilamide, N¹-(pyrazinyl)-, benzenesulfonamide, 4-amino-N-2-pyrazinyl-
• CAS: 116-44-9

Description

Pyrimethamine is an antimicrobial agent that inhibits the growth of microorganisms by inhibiting their synthesis of folic acid, a vitamin necessary for cell division. This drug also has been used to treat toxoplasmosis and other protozoal infections. Pyrimethamine is active against trypanosomes and the erythrocytic forms of malaria parasites. It is given orally or intravenously in combination with sulfadiazine or sulfapyrazine for treatment of toxoplasmosis, malaria, and some protozoal infections. Pyrimethamine can be administered by intramuscular injection or as a suppository for treatment of choroidal neovascularization in patients with age-related macular degeneration. It is also used as a pharmacological agent in glucose tolerance tests. The most common side effects are gastrointestinal disturbances, including nausea and vomiting, abdominal pain, and diarrhea. Other adverse reactions include blood disorders (thrombocytopen

• Brand: Biosynth

Chemical properties

• Molecular weight: 250.28 g/mol
• Formula: C₁₀H₁₀N₄O₂S
• Purity: Min. 95%
• InChI: InChI=1S/C10H10N4O2S/c11-8-1-3-9(4-2-8)17(15,16)14-10-7-12-5-6-13-10/h1-7H,11H2,(H,13,14)
• InChI key: InChIKey=YEAICDDXRUOCKJ-UHFFFAOYSA-N
• SMILES: Nc1ccc(S(=O)(=O)Nc2cnccn2)cc1