4-Amino-1-methylpiperidine-4-carboxylic acid

CAS: 15580-66-2

Ref. 3D-FA124850

Product Information

• Name: 4-Amino-1-methylpiperidine-4-carboxylic acid
• Synonyms: 4-piperidinecarboxylic acid, 4-amino-1-methyl-, 4-Piperidinecarboxylic Acid, 4-Amino-1-Methyl-, Isonipecotic acid, 4-amino-1-methyl-, NSC 117761

Description

4-Amino-1-methylpiperidine-4-carboxylic acid (4AMP) is a potent inhibitor of the enzyme kallikrein, which is responsible for the degradation of kinins. Kinins are important mediators of inflammation and pain. 4AMP has been shown to inhibit the uptake of amino acids by cells, including lysine and phenylalanine, in cell membrane preparations. The inhibition of these amino acids may lead to an accumulation in extracellular fluid. This accumulation may have an effect on the transport of other molecules across cell membranes, such as ornithine and arginine.

• Brand: Biosynth

Chemical properties

• Molecular weight: 158.2 g/mol
• Formula: C₇H₁₄N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C7H14N2O2/c1-9-4-2-7(8,3-5-9)6(10)11/h2-5,8H2,1H3,(H,10,11)
• InChI key: InChIKey=PRROBIIYGSUPNR-UHFFFAOYSA-N
• SMILES: CN1CCC(N)(C(=O)O)CC1