3-Aminocoumarin
CAS: 1635-31-0
Ref. 3D-FA13065
1g | Discontinued | ||
2g | Discontinued | ||
5g | Discontinued | ||
250mg | Discontinued | ||
500mg | Discontinued |
Product Information
- 3-Amino-2H-chromen-2-one3-Coumarinamin3-Amino-2-benzopyrone
- 2H-1-Benzopyran-2-one, 3-amino-
- 3-Amino-2H-1-benzopyran-2-one
- 3-Amino-chromen-2-one
- 3-Aminochromen-2-one
- 3-Coumarinamine
- 3-amino-2H-chromen-2-one
- Coumarin, 3-amino-
3-Aminocoumarin is a coumarin derivative that inhibits the activity of dipeptidyl peptidase IV (DPP-IV), an enzyme that degrades the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). 3-Aminocoumarin has been shown to inhibit tumor growth and induce apoptosis in cancer cells. It also binds to copper, which may be related to its anticancer activity. 3-Aminocoumarin is a chiral compound that can exist as either of two enantiomers: L and D. The L form is considered more potent than the D form.
3-Aminocoumarin can be synthesized by reacting malic acid with a phenylacetic acid derivative in the presence of ammonia or ammonium hydroxide.