4-Amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide

CAS: 127-79-7

Ref. 3D-FA133240

Product Information

• Name: 4-Amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
• Synonyms: benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, 2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine, 2-Sulfa-4-methylpyrimidine, 2-Sulfanilamido-4-methylpyrimidine, 2-Sulfanylamido-4-methylpyrimidine, 2-Sulphanilamido-4-methylpyrimidine, 2632Rp, 2643Rp, 4-Amino-N-(4-methyl-2-pyrimidinyl)benzenesulfonamide, 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide, A 310, Benzenesulfonamide, 4-Amino-N-(4-Methyl- 2-Pyrimidinyl)-, Cremomerazine, Debenal-M, Kelamerazine, Mebacid, Mesulfa, Methylpyrimal, Methylsulfazine, Metilsulfadiazin, Metilsulfazin, N-(4-Methyl-2-pyrimidyl)sulfanilamide, N-(4-Methylpyrimidin-2-yl)-4-aminobenzenesulfonamide, N1-(4-Methyl-2-pyrimidinyl)sulfanilamide, N1-(4-methylpyrimidin-2-yl)sulphanilamide, N¹-(4-Methyl-2-pyrimidinyl)sulfanilamide, Nsc 27259, Percoccide, Pirimal-M, Pyralcid, Pyrimal m, Romezin, Rp 2632, Septacil, Spanbolet II, Sulfameradine, Sulfamerazin, Sulfamerazina, Sulfamerazine, Sulfamerazine Ph Fr-Fu-Usp, Sulfamerazine solution, Sulfamethyldiazine, Sulfanilamide, N1-(4-methyl-2-pyrimidinyl)-, Sulfanilamide, N¹-(4-methyl-2-pyrimidinyl)-, Sulphamerazine, Sumedine, Veta-Merazine

Description

4-Amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide (AMBPS) is a sulfonamide antimicrobial agent that belongs to the group of sulfa drugs. It is a potent inhibitor of tetracycline resistance in bacterial cells, and has been shown to be effective against infectious diseases such as tuberculosis, leprosy and pneumonia. AMBPS has also been used in wastewater treatment and biological studies with high values. This drug binds to sulfamerazine, which inhibits bacterial growth by inhibiting RNA synthesis. The hydrogen bonding interactions between AMBPS and sulfadiazine are thought to be responsible for the effects on congestive heart failure.

• Brand: Biosynth

Chemical properties

• Molecular weight: 264.3 g/mol
• Formula: C₁₁H₁₂N₄O₂S
• Purity: Min. 95%
• InChI: InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
• InChI key: InChIKey=QPPBRPIAZZHUNT-UHFFFAOYSA-N
• SMILES: Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1