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6-Amino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
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6-Amino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

CAS: 16837-08-4

Ref. 3D-FA133788

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Estimated delivery in United States, on Tuesday 18 Feb 2025

Product Information

Name:
6-Amino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
Synonyms:
  • 4(1H)-pyrimidinone
  • 6-amino-2,3-dihydro-1-methyl-2-thioxo-
  • 6-Amino-2,3-dihydro-1-methyl-2-thioxo-4(1H)-pyrimidinone
  • 6-amino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
  • NSC 43406
  • Uracil, 6-amino-1-methyl-2-thio-
  • 4(1H)-Pyrimidinone, 6-amino-2,3-dihydro-1-methyl-2-thioxo-
Description:

6-Amino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (6AMT) is a synthetic compound that inhibits bacterial growth. It is a prodrug that is hydrolyzed in vivo to its active form, 6-amino-1-(methylamino)-2-(thio)pyrimidin-4(1H)-one (6AME). 6AMT and 6AME inhibit the synthesis of cellular proteins by inhibiting sulfate adenylyltransferase and ribonucleoside diphosphate reductase. These enzymes are necessary for the synthesis of purines and pyrimidines, which are essential components of DNA and RNA. The antimicrobial activity of 6AMT may be due to its ability to chelate metal ions such as copper or iron, which are important in many bacterial metabolic processes.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
157.19 g/mol
Formula:
C5H7N3OS
Purity:
Min. 95%
InChI:
InChI=1S/C5H7N3OS/c1-8-3(6)2-4(9)7-5(8)10/h2H,6H2,1H3,(H,7,9,10)
InChI key:
InChIKey=CIMIOUTTYHCOJU-UHFFFAOYSA-N
SMILES:
Cn1c(N)cc(=O)[nH]c1=S
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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