5-(Acetylamino)-2-aminobenzoic acid

CAS: 50670-83-2

Ref. 3D-FA133810

Product Information

• Name: 5-(Acetylamino)-2-aminobenzoic acid
• Synonyms: benzoic acid, 5-(acetylamino)-2-amino-, 1-Amino-2-carboxy-4-acetamidobenzene, 2-Amino-5-Acetamino Benzoic Acid, 2-Amino-5-acetamidobenzoic acid, 5-(Acetylamino)-2-Aminobenzoic Acid, 5-(N-Acetylamino)anthranilic acid, 5-Acetamide-2-Amino-Benzoic Acid, 5-Acetamidoanthranilic acid, 5-Acetylamino anthranilic acid, 5-Acetylaminoanthranilic acid, Benzoic acid, 5-(acetylamino)-2-amino-, Benzoic acid, 5-acetamido-2-amino-
• CAS: 50670-83-2

Description

5-(Acetylamino)-2-aminobenzoic acid is a potential drug candidate. It has been shown to inhibit the activity of thrombin and may be an antithrombotic agent. The compound has low activity against thrombin and the substituents on the phenyl ring have little effect on this property. 5-(Acetylamino)-2-aminobenzoic acid inhibits blood coagulation by inhibiting the activation of prothrombin, which prevents the formation of fibrin clots. The substituents on the furanyl ring are electronegative and can form hydrogen bonds with other molecules in solution, which may explain its good selectivity for thrombin over other enzymes such as trypsin or chymotrypsin.

• Brand: Biosynth

Chemical properties

• Molecular weight: 194.19 g/mol
• Formula: C₉H₁₀N₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C9H10N2O3/c1-5(12)11-6-2-3-8(10)7(4-6)9(13)14/h2-4H,10H2,1H3,(H,11,12)(H,13,14)
• InChI key: InChIKey=GSOHXJQXAKNJES-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc(N)c(C(=O)O)c1