5-Amino-3-pyridinecarboxamide

CAS: 60524-14-3

Ref. 3D-FA143707

Product Information

• Name: 5-Amino-3-pyridinecarboxamide
• Synonyms: 3-Pyridinecarboxamide, 5-Amino-, 5-Aminonicotinamide

Description

5-Amino-3-pyridinecarboxamide is an analog of nicotinamide that has been shown to have tumor-modulating activity. It has been shown to inhibit the growth of tumor cells in a maximally tolerated dose and inhibits hypoxic tumor growth. 5-Amino-3-pyridinecarboxamide is also structurally related to 6-methylmercaptopurine, which has been shown to induce tumor regression, but without the toxic side effects of 6-methylmercaptopurine. Studies have shown that 5-amino-3 pyridinecarboxamide inhibits the proliferation of breast cancer cells by inhibiting riboside synthesis, which may be due to its structural similarity to adriamycin, an antitumor antibiotic.

• Brand: Biosynth

Chemical properties

• Molecular weight: 137.14 g/mol
• Formula: C₆H₇N₃O
• Purity: Min. 95%
• InChI: InChI=1S/C6H7N3O/c7-5-1-4(6(8)10)2-9-3-5/h1-3H,7H2,(H2,8,10)
• InChI key: InChIKey=GQGQFLVAXGKVQL-UHFFFAOYSA-N
• SMILES: NC(=O)c1cncc(N)c1