![1-Acetyl-5-bromo-3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-1H-indole](https://static.cymitquimica.com/products/3D/img/FA152552.png "Click to enlarge")
1-Acetyl-5-bromo-3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-1H-indole
CAS: 205369-12-6
Ref. 3D-FA152552
| 2mg | Discontinued | ||
| 5mg | Discontinued | ||
| 10mg | Discontinued | ||
| 25mg | Discontinued | ||
| 50mg | Discontinued |
Product Information
Name:
1-Acetyl-5-bromo-3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-1H-indole
Description:
1-Acetyl-5-bromo-3-[(2R)-1-methylpyrrolidin-2-yl]methyl]-1H-indole is a potent and selective antagonist of the type II metabotropic glutamate receptor (mGluR2). 1ABRMMI has a conformation that is mediated by steric and amide groups. The nitrogen atom in the indole ring is coordinated with two hydrogen atoms and one oxygen atom from the acetyl group. The crystal structure of 1ABRMMI reveals that it binds to the active site of mGluR2, which contains a binding pocket for an azepane or ketone group. This drug was found to be prophylactic against convulsions induced by pentylenetetrazol.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
335.24 g/mol
Formula:
C16H19BrN2O
Purity:
Min. 95%
InChI:
InChI=1S/C16H19BrN2O/c1-11(20)19-10-12(8-14-4-3-7-18(14)2)15-9-13(17)5-6-16(15)19/h5-6,9-10,14H,3-4,7-8H2,1-2H3/t14-/m1/s1
InChI key:
InChIKey=PIIFSFIOOCHDIK-CQSZACIVSA-N
SMILES:
CC(=O)n1cc(C[C@H]2CCCN2C)c2cc(Br)ccc21
MDL:
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