2-Azido-6-benzylaminopurine
CAS: 61716-00-5
Ref. 3D-FA152901
| 2mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
2-Azido-6-benzylaminopurine is a bioassayable analog of 6-benzylaminopurine that has been used in the study of receptor protein binding. It has been found to be an agonist for the benzodiazepine site on the GABA receptor, which is responsible for its physiological effects. 2-Azido-6-benzylaminopurine binds to the benzodiazepine receptor and stimulates chloride ion influx, which leads to chloride ion accumulation and membrane depolarization. This process opens voltage gated calcium channels, which allows calcium ions to enter the cell and stimulate protein synthesis. The effect can be reversed by removing extracellular chloride ions with a chelating agent or by blocking voltage gated calcium channels with a local anesthetic.
Chemical properties
Technical inquiry about: 3D-FA152901 2-Azido-6-benzylaminopurine
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