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Alcaftadine
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Alcaftadine

CAS: 147084-10-4

Ref. 3D-FA163251

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Estimated delivery in United States, on Wednesday 15 Jan 2025

Product Information

Name:
Alcaftadine
Synonyms:
  • 6,11-Dihydro-11-(1-methyl-4-piperidinylidene)-5H-imidazo[2,1-b][3]benzazepine-3-carboxaldehyde
  • 11-(1-Methylpiperidin-4-ylidene)-5,6-dihydroimidazo[2,1-b][3]benzazepine-3-carbaldehyde
  • 5H-Imidazo(2,1-b)(3)benzazepine-3-carboxaldehyde, 6,11-dihydro-11-(1-methyl-4- piperidinylidene)-
  • Lastacaft
  • R 89674
  • Unii-7Z8O94Ecsx
Description:

Alcaftadine is a selective histamine H1 receptor antagonist. It inhibits the action of histamine on its receptor, thereby reducing the symptoms of an allergic reaction. Alcaftadine is metabolized by hydrolysis to an acylated derivative which undergoes an acylation reaction with a nucleophilic amino acid in the presence of hydrochloric acid. The drug interacts with other drugs that are metabolized by cytochrome P450 3A4, such as benzodiazepines and anticonvulsants. Alcaftadine has a long half-life, ranging from 16 to 30 hours, and is eliminated in urine unchanged or as metabolites. It also has pharmacokinetic properties that may be affected by polymorphism at the 2-adrenergic receptor gene locus (DRD2).

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
307.39 g/mol
Formula:
C19H21N3O
Purity:
Min. 95%
InChI:
InChI=1S/C19H21N3O/c1-21-9-6-15(7-10-21)18-17-5-3-2-4-14(17)8-11-22-16(13-23)12-20-19(18)22/h2-5,12-13H,6-11H2,1H3
InChI key:
InChIKey=MWTBKTRZPHJQLH-UHFFFAOYSA-N
SMILES:
CN1CCC(=C2c3ccccc3CCn3c(C=O)cnc32)CC1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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